Find conserved regions across your protein sequences.
Aligns protein sequences, saves the alignment locally, and interprets conservation and similarity for the user's research objective.
When to use it
Use to assess similarity, domain conservation, or key residue conservation across multiple protein sequences, not for database searches, non-protein sequences, structural alignment, or a single sequence.
Give it a FASTA file containing multiple protein sequences; it saves a local alignment and reports an interpretation addressing your research objective.
What you provide
Requires uv installed and on PATH, with setup handled through the uv skill.
The alignment wrapper requires Python 3.10 or newer.
This skill
EBI Clustal Omega
Starts a remote alignment job
Uploads protein sequences and email
~/.env
Creates a home environment file